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Tackling Multidrug-Resistant E. coli: A Dual Strike Approach using a phage cocktail and a host-targeting molecule | Canal U
Description of a novel approach to combat multidrug-resistant E. coli ST131 by combining a cocktail of bacteriophages with the C910 compound, which inhibits host cell invasion. This strategy demonstrated synergistic effects in vitro and improved efficacy in a mouse model, offering a potential solution for reducing gut colonization and tissue ...
Apr 25, 2024
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