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The Massachusetts General Hospital acute stroke imaging algorithm: an experience and evidence based approach

Neuroradiology Division, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA Correspondence to Dr R G González, Neuroradiology Division, Massachusetts General Hospital, ...
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Reinitiating anticoagulation in chronic subdural hematomas: does adding middle meningeal artery embolization add value? A multi-institutional, multinational database study

Background The safety of early anticoagulation in chronic subdural hematoma (cSDH) patients treated with surgery, with or without middle meningeal artery embolization (MMAE), remains unclear. This ...
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Outcomes of flow diversion in intracranial aneurysms accompanied by parent artery stenosis

Background The impact of parent artery stenosis on the treatment of intracranial aneurysms by using flow diversion (FD) remains unknown. This multicenter retrospective study aimed to evaluate the ...
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Republished: Real-time MRI guidance for intra-arterial drug delivery in a patient with a brain tumor: technical note

Patients suffering from malignant brain tumors are burdened with a grim prognosis. The blood brain barrier is considered a primary obstacle in therapeutic drug delivery to the brain. Intra-arterial ...
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Hematoma evacuation modifies the relationship between early changes in neutrophil-to-lymphocyte ratio and mortality after intracerebral hemorrhage

Background Neutrophil-to-lymphocyte ratio (NLR) is a prognostic indicator in intracerebral hemorrhage (ICH) thought to reflect systemic inflammation driving secondary brain injury. Recent evidence ...
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Occlusion site and outcomes in intra-arterial tenecteplase after successful endovascular therapy: a secondary analysis of the ANGEL-TNK trial

Background Endovascular thrombectomy achieves macroreperfusion in large vessel occlusion (LVO) stroke, but only one-quarter of patients had excellent functional outcome. Adjunct intra-arterial (IA) ...
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Middle meningeal artery embolization as a surgical adjunct for non-acute subdural hematoma: real world outcomes and treatment effect heterogeneity

Background Middle meningeal artery embolization (MMAE) is a promising treatment for non-acute subdural hematoma (NASDH), but trial evidence is limited by heterogeneity and open label design bias. This ...
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Safety and efficacy of selective and superselective intra-arterial cerebral infusion with blood–brain barrier disruption for glioma: a systematic review and meta-analysis

Background Selective and superselective intra-arterial cerebral infusion (SIACI/SSIACI) delivers chemotherapy directly to tumor-supplying arteries, achieving high local drug levels with reduced ...
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Subclavian loop catheterization technique (SLOT): novel transradial salvage technique for challenging vertebral artery ostial stenosis

Objective To evaluate the efficacy and safety of the subclavian loop catheter technique for endovascular stenting of vertebral artery ostial stenosis (VAOS). Methods We retrospectively reviewed all ...
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Acute ischemic stroke and reperfusion drive molecular immune-vascular activations detectable in peripheral blood

Background Inflammation drives damage in acute ischemic stroke (AIS). Here, we map temporal and molecular mechanisms of immune-vascular response in patients with AIS treated with endovascular ...
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Comparison between contact aspiration alone and combined thrombectomy for intracranial internal carotid artery occlusion: insights from SARA-3 registry

Background Acute intracranial internal carotid artery (ICA) occlusion lowers first-pass reperfusion rates and clinical outcomes. Aspiration catheter and stent-retriever thrombectomy (CA+SR) is ...
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Early clinical experience with the Emboguard Balloon Guide Catheter: impact on technical success and patient outcomes in large vessel occlusion thrombectomy

Background This study evaluated the performance of the newer-generation Emboguard Balloon Guide Catheter (EBGC) in treating anterior circulation large vessel occlusions (LVOs). Methods A prospectively ...