Risk stratification in compensated advanced chronic liver disease has traditionally been based on the identification of ...
Diambra and colleagues1 integrated metabolic dysfunction-associated steatotic liver disease phenotypes with proteomics to derive a four-protein mortality score (PS4: FTCD, FABP1, ADGRG1 and GAST). We ...
The potential of dietary interventions as a therapy for IBDs is increasingly appreciated in clinical practice. A central role ...
Snijkers and colleagues should be congratulated for completing a multicentre, three-arm randomised trial of gut-directed ...
Background Fistulising perianal Crohn’s disease (CD) remains a debilitating condition, with few randomised controlled trials conducted so far. Objective To evaluate the efficacy and safety of ...
Background New-onset diabetes (NOD) increases the risk of pancreatic cancer. Previous studies have mainly focused on the presence or absence of diabetes, with limited attention to NOD severity at ...
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Background Irritable bowel syndrome (IBS) is a disorder of gut-brain interaction, with some recommended treatments targeting brain-gut axis dysfunction. Objective To compare relative efficacy of ...
Despite the transformative impact of immune checkpoint inhibitors in oncology, hepatocellular carcinoma (HCC) remains stubbornly resistant in many patients, with durable responses to combination ...
Background Gut microbiota has been widely recognised as playing a critical role in maintaining immune imbalance and the development of rheumatoid arthritis (RA). As key roles mediating interkingdom ...
Crohn’s disease (CD) is a chronic inflammatory disorder of the gastrointestinal tract with high risk of surgery. Despite advances in medical treatment, of those patients who undergo ileocolonic ...