Back-to-back blowout losses and another injury to star back Christian McCaffrey might just be the final blow to the dwindling ...

Christian McCaffrey was tearing it up against the Bills before exiting early in the second quarter with a knee injury.

The return of a superstar may be short lived. It was a snowy night in Buffalo, New York when the San Francisco 49ers took on ...

Kyle Shanahan said that Christian McCaffrey did injure his PCL and it is a 6-week recovery. His season now looks like it’s ...

SANTA CLARA, CALIFORNIA - JANUARY 22: Christian McCaffrey #23 of the San Francisco 49ers rushes for a touchdown against the ...

The San Francisco 49ers' season has been on the brink for weeks, and the Week 13 blowout loss to the Buffalo Bills certainly ...

The 49ers are down to one healthy RB, rookie Isaac Guerendo. They will likely elevate Patrick Taylor Jr. from the practice ...

The San Francisco 49ers' dreadful season got worse in Week 13 when running backs Christian McCaffrey and Jordan Mason both ...

It's going to be another lost season for Christian McCaffrey, but he is not the only San Francisco running back who suffered ...

The San Francisco 49ers entered Sunday night's matchup against the Buffalo Bills at Highmark Stadium without several key ...

Head coach Kyle Shanahan shared the latest injury and team updates emerging from the San Francisco 49ers Week 13 matchup ...