. For about a century, the argument for focusing on rare Mendelian disorders was as follows: Mendelian phenotypes will reveal genes involved in common multifactorial traits, metabolic pathways ...

Gait disorders in Parkinson's disease is one of the most difficult symptoms to manage. Due to the burstiness and randomness of gait disorders, there are some uncertainties and subjectivities during ...

Functional neurological disorder (FND) is a prevalent, disabling and costly condition at the neurology–psychiatry intersection. After being marginalised in the late 20th century, there has been ...

Klinge, Marmarou, Bergsneider, Relkin, and Black (2005) reviewed the literature dating back to 1966, and found that gait improvement after shunting ranged from 30% to 95%.

Normal pressure hydrocephalus is a treatable condition for many patients. The assessment findings in NPH include a distinctive gait abnormality and disturbances in cognition and control of urine ...

Neurorehabilitation with robotic devices requires a paradigm shift to enhance human-robot interaction. The coupling of robot assisted gait training (RAGT) with a brain-machine interface (BMI) ...

Coronary Artery Disease; Myocardial Infarction; Epidemiology; Risk Factors; Stroke; Legalisation of medical and recreational cannabis commerce is spreading around the world, associated with increased ...

Recessive mutations in POLR3A exhibit considerable phenotypic diversity, spanning from severe childhood-onset hypomyelinating leukodystrophic syndrome to less severe gait disorders, which may present ...

OBJECTIVE: To identify gait patterns in a large group of children with diplegic cerebral palsy and to characterize each group according to age, Gross Motor Function Classification System (GMFCS) level ...

A novel blood test could help diagnose celiac disease more straightforwardly, without the need to potentially trigger symptoms.

Over-the-counter supplement could prevent heart disease in type 2 diabetes patients by Kaamya Mehta, British Heart Foundation edited by Lisa Lock , reviewed by Andrew Zinin ...

The Ethical Minefield of Testing Infants for Incurable Diseases. Screening can now determine their risk for an ever-growing list of conditions — including ones we can’t do much about.