Life's instructions are written in DNA, but it is the enzyme RNA polymerase II (Pol II) that reads the script, transcribing ...

The discovery of obelisks is forcing scientists to rethink the limits of life's smallest genomes. These tiny RNA circles, hiding in the human mouth and gut, expand the known diversity of replicating ...

For decades, biologists treated DNA as a static string of letters, a linear code that cells read like text on a page. A new ...

Researchers at Children's Hospital of Philadelphia (CHOP) and Children's National Hospital in Washington D.C. are uncovering how rare inherited genetic variants contribute to the development of brain ...

The iSNP systems genomics pipeline models how non-coding SNPs cumulatively impact cellular signalling and gene regulatory networks, revealing patient-specific mechanisms linking disease-associated ...

A new paper from the University of Kansas overturns the idea that a "risk gene" carried by millions of people worldwide ...

Analysis of 135,000 participants reveals 11 genetic regions tied to delayed gratification and shows shared biology with ...

Pyrrolysine is an important component of methyltransferase enzymes, which the archaea use to metabolize methylamine in the environment. “The need for that metabolism and availability of the machinery ...

A new study shows that RNA splicing, not just gene expression, holds powerful clues to why some mammals live far longer than ...

This study presents a valuable tool named TSvelo, a computational framework for RNA velocity inference that models transcriptional regulation and gene-specific splicing. The evidence supporting the ...

Scientists found that golden retrievers and humans share many emotion related genes, helping explain learning differences in both species.

Researchers have identified a stress-activated control mechanism that helps breast cancer cells reshape gene activity to ...