Everyone recognizes the bald cancer patient motif. It’s usually a woman wearing a scarf to cover her shiny head. It is supposed to signify struggle and courage in the face of misfortune.

Using the developed algorithm and information from The Cancer Genome Atlas (TCGA), the researchers found that the highest rate of mutation occurs in the AGC kinase motif called RxRxxS/T. RxRxxS/T ...

Scientists identified the mechanism by which a sea cucumber molecule inhibits sulfatase-2, an enzyme that’s often upregulated ...

Innovative study of DNA's hidden structures may open up new approaches for treatment and diagnosis of diseases, including cancer.

A related G-quadruplex-targeted agent, CX-5461, is now in trials for breast cancer. I-motifs form when sets of cytosines pair with protonated cytosines, connecting U-shaped DNA strands.

Much of our knowledge of the protein PD-1, a leading cancer treatment target, comes from studies in mice. In a comprehensive assessment of PD-1, researchers have found that PD-1 in mice is ...