3 Joint Shantou International Eye Center, Shantou University and Chinese University of Hong Kong, Shantou, China Background/aims To investigate the clinical features of Chinese patients with ...

The FDA agreed that the design of a Phase 3 trial testing privosegtor in optic neuritis could support a future approval ...

Background Antibodies against glycine receptors (GlyR Ab) have been strongly linked to progressive encephalomyelitis with rigidity and myoclonus (PERM). Their association with other neurological ...

Background Patients with anti-aquaporin-4 antibody seropositive (AQP4-IgG+) neuromyelitis optica spectrum disorders (NMOSDs) frequently suffer from optic neuritis (ON) leading to severe retinal ...

Sex differences in NMOSD go beyond the notable female predominance, affecting the course of the disease and response to therapeutics. Evidence consistently shows that autoimmune disorders tend to ...

Please provide your email address to receive an email when new articles are posted on . Become familiar with antibody-mediated myelin oligodendrocyte glycoprotein and neuromyelitis optica spectrum ...

Immune profiles in AQP4 optic neuritis differ by disease phase, with distinct cell roles and pathways linked to vision. The immune response in patients with AQP4 antibody-positive optic neuritis (AQP4 ...

Comorbidities, especially cardiovascular and autoimmune diseases, were frequent in aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (AQP4-NMOSD) and myelin oligodendrocyte ...

The following is a summary of “Comorbidities Are Associated With Unfavorable Outcome in Aquaporin-4 Antibody Positive Neuromyelitis Optica Spectrum Disorders and Myelin Oligodendrocyte Glycoprotein ...

NMOSD causes severe ocular effects, including optic neuritis, leading to vision loss and impacting quality of life. Early AQP4-IgG testing and neurology referrals are crucial for differentiating NMOSD ...

ABSTRACT: Optic neuritis (ON) is a kind of inflammatory disease characterized by optic nerve damage, which can lead to vision loss or even blindness. With the development of ON pathology, the medical ...

Early diagnosis of NMOSD is key to preventing disability, improving survival. Neuromyelitis optica spectrum disorder (NMOSD) is a rare, antibody (Ab)-mediated, inflammatory autoimmune disorder of the ...