"Patients with anti-AQP4-Ab may basically need long-term relapse prevention, because they surely experience much higher relapse activity, with much worse neurological disturbance…In MOGAD patients, ...

In an exploratory study, serum levels of glial fibrillary acidic protein (GFAP) appeared to be predictive of disease severity and prognosis in patients with aquaporin-4 (AQP4)-immunoglobulin G (IgG) ...

Clinical Presentation Common symptoms of NMOSD result from damage to the optic nerve, spinal cord, and brainstem. These include optic neuritis with symptoms of loss or blurred vision in 1 or both eyes ...

Diagnoses in the MS group included relapsing-remitting MS in 26; secondary progressive MS in 1; and primary progressive MS in 1. Diagnoses in the OND group included acute demyelinating ...

Comorbidities, especially cardiovascular and autoimmune diseases, were frequent in aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder (AQP4-NMOSD) and myelin oligodendrocyte ...

TOKYO--(BUSINESS WIRE)--Chugai Pharmaceutical Co., Ltd. (TOKYO:4519) announced that the results of the SAkuraSky Study (NCT02028884), a global phase III clinical study of satralizumab (development ...

Researchers have identified a molecular suspect in a disorder similar to multiple sclerosis (MS) that attacks the optic nerve and spinal cord, according to a report presented at the 130th annual ...

A 34-year-old woman with a history of multiple sclerosis and prior optic neuritis in the right eye presented to the neuro-ophthalmology clinic with 3 days of pain with eye movement and mildly ...

ROCHESTER, Minn. -- Mayo Clinic has launched a first-in-the-U.S. clinical test that will help patients who recently have been diagnosed with an inflammatory demyelinating disease (IDD) but may be ...

The retina is an extension of the brain. Like the brain, neurodegeneration of the retina occurs with age and is the cause of several retinal diseases including optic neuritis, macular degeneration, ...