Aaron Donald's status for Week 1 is up in the air, but Todd Gurley thinks (and hopes) he'll play against the 49ers.

San Francisco 49ers pass rusher Keion White has said he plans to "OD on melatonin" in an effort to help combat the jet lag of ...

The San Francisco 49ers announced on Friday that they ruled out defensive lineman Sam Okuayinonu ahead of their Week 1 ...

That was a clear sign Okuayinonu would likely not be hopping on a later plane to join the team and make his season debut, and the 49ers have now downgraded him to out. It is a significant setback at a ...

The longest road trip in NFL history is about to turn into a fascinating experiment in travel strategy. The San Francisco ...

When the Los Angeles Rams and San Francisco 49ers run onto the Melbourne Cricket Ground in a week's time, they will be the ...

The 49ers will not have defensive end Sam Okuayinonu in their Thursday night opener against the Rams in Australia.

The NFL regular season opens when the defending Super Bowl champion Seattle Seahawks host the New England Patriots on ...

The 49ers have arrived in Melbourne for their season-opening NFL game against the Rams at the Melbourne Cricket Ground on ...

Thursday didn’t exist for Kyle Shanahan and the 49ers. They boarded a two-story jumbo jet a little before midnight Wednesday ...

One of Test cricket's greats talks growing the game, his concern over the Australian top order and 'Clicky' Ponting ...

The majority of NFL Thursday Night Football games will air on Prime Video. The first Thursday night game, however, the San ...