Literature reviews are an important part of research as they precede a doctoral dissertation, a master’s thesis, a policy paper with recommendations, a single scientific publication, a white paper, a ...

Vitamin C (vitC) plays critical roles in numerous biological processes. Its potential therapeutic applications encompass metabolism, age-related diseases, and other associated biological processes [2, ...

Main article text Human immunodeficiency virus (HIV), particularly HIV-1, is the primary cause of the global AIDS pandemic. Each year, millions of new HIV infections and hundreds of thousands of ...

FGF-23 expression is elevated in patients with AF and reduced left atrial appendage emptying velocity (LAAev). In these patients, FGF-23 might promote cardiogenic stroke by reducing LAAev. We ...

Phosphodiesterase-4 (PDE4), a member of the phosphodiesterase superfamily, has highly important roles in cyclic nucleotide signaling pathways and a variety of skin disorders. Blocking PDE4 activity ...

Acute myocardial infarction (MI), a critical and dangerous manifestation of coronary heart disease resulting from arterial or bypass graft thrombosis, rapidly induces myocardial ischemia and hypoxia, ...

Acute pulmonary embolism (PE) remains a global health challenge with significant morbidity and mortality. High-risk PE, characterized by hemodynamic instability, and intermediate-risk PE, with ...

Infectious diseases pose a major challenge to public health worldwide. In recent years, vector-borne and zoonotic diseases have emerged as major public health threats. Effective prevention, control, ...

Tuberculosis is a global public health problem: approximately one-quarter of the world’s population is infected with Mycobacterium tuberculosis, and more than 10 million new cases occur per year.

Many studies have reported that obesity causes heart failure (HF) pathogenesis. The elevated circulating levels of angiopoietin-like protein 2 (ANGPTL2) observed in patients with HF suggest potential ...

Background: With distal transradial access (dTRA), the postoperative compression time remains significantly longer than the recommended range via in practice. This study investigated whether ...

Proteins are essential macromolecules that perform functions according to their conformational dynamics. Studying the conformational changes induced by protein mutations is the standard approach used ...