A 46-year-old man with CKD presented with a 2-year history of painless shortening and rounding of the fingertips. Radiographs of the hands showed resorption of the terminal tufts of all the distal ...

Whether catheter-directed thrombolysis improves clinical outcomes in patients with intermediate-high–risk pulmonary embolism, ...

Approximately one half of patients undergoing transcatheter aortic-valve implantation (TAVI) have concomitant coronary artery ...

In patients with syncope who present to the emergency department for evaluation, diagnosing an underlying cardiac arrhythmia ...

Pulmonary hypertension that is caused by left heart disease and is associated with heart failure may be driven by sympathetic ...

Patients are at increased risk for recurrent ischemic events after an acute coronary syndrome event. Milvexian, an oral ...

Atherosclerosis may begin in early adulthood and remain clinically silent for decades before cardiovascular disease manifests. Although silent atherosclerosis is associated with cardiovascular ...

The effect of clopidogrel monotherapy as compared with extended dual antiplatelet therapy (DAPT) with clopidogrel and aspirin ...

In states with abortion bans, clinicians and hospitals should reduce harm by maximizing care to the extent legally possible, thereby recentering medical expertise and commitment to ...

The safety of omitting up-front treatment with aspirin during primary percutaneous coronary intervention (PCI) in patients with ST-segment elevation myocardial infarction (STEMI) remains unclear.

Whether prasugrel or ticagrelor should be the preferred P2Y12 inhibitor for patients with an acute coronary syndrome is uncertain. We conducted a registry-based, open-label, stepped-wedge, ...

Nonobstructive hypertrophic cardiomyopathy (HCM) is a common condition that is associated with substantial morbidity and no ...