Journal of Nuclear Medicine

Targeted Radiopharmaceutical Therapy: Advances, Investment Dynamics, and Future Directions—Part 2

Radiopharmaceutical therapy is rapidly expanding, propelled by scientific and investment momentum. This paper analyzes the ...
Journal of Nuclear Medicine

How Following Medical Artificial Intelligence Advice Can Mitigate Malpractice Liability: Cross-National Insights from a Randomized Trial

Artificial intelligence (AI) increasingly influences clinical decision-making, yet its recommendations may diverge from ...
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Molecular Imaging of Mechanisms of Impaired Cardiac Repair After Macrophage Depletion in Mice: A Longitudinal Multitracer Imaging Study

Journal of Nuclear Medicine June 2026, jnumed.125.271856; DOI: https://doi.org/10.2967/jnumed.125.271856 We hypothesized that CCR2-targeted imaging would better ...
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Diagnostic Performance of FAPI PET in Patients with Breast Cancer: A Systematic Review

Journal of Nuclear Medicine May 2026, jnumed.126.272191; DOI: https://doi.org/10.2967/jnumed.126.272191 ...
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Initial Clinical Experience with [ 177 Lu]Lu-RTX-2358 Radiopharmaceutical Therapy Targeting Fibroblast Activation Protein: Biodistribution, Pharmacokinetics, and Dosimetry

This series of case studies provides the first clinical experience with the fibroblast activation protein-α (FAP)–targeting radiopharmaceutical [177Lu]Lu-RTX-2358 in patients with advanced solid ...
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Preclinical and First-in-Human Study of Carbonic Anhydrase IX–Targeting Theranostic Pair, [

Journal of Nuclear Medicine April 2026, jnumed.125.271604; DOI: https://doi.org/10.2967/jnumed.125.271604 ...
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Development of Dar3A Chelator and Construction of FAP-Targeted PET Probe as Proof of Concept and for First-in-Human Evaluation

Journal of Nuclear Medicine April 2026, jnumed.125.271421; DOI: https://doi.org/10.2967/jnumed.125.271421 ...
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Risk Assessment in Large B-Cell Lymphoma Using Metabolic Tumor Volume: Real-World Data from a Multicenter Cohort of Patients Undergoing CAR T-Cell Therapy

Journal of Nuclear Medicine March 2026, jnumed.125.271976; DOI: https://doi.org/10.2967/jnumed.125.271976 ...
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Single-Domain Antibody Probe with Low Renal Uptake for Claudin 18.2–Targeted PET Imaging of Gastric Cancer: Preclinical and Pilot Clinical Evaluations

Journal of Nuclear Medicine March 2026, jnumed.125.271704; DOI: https://doi.org/10.2967/jnumed.125.271704 ...
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Assessment of CCR2 PET as a Biomarker for Head and Neck Squamous Cell Carcinoma

Journal of Nuclear Medicine March 2026, jnumed.125.271601; DOI: https://doi.org/10.2967/jnumed.125.271601 ...
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Influence of Subcellular Localization on the Cytotoxicity of Targeted α-Therapy

Journal of Nuclear Medicine December 2025, jnumed.125.270175; DOI: https://doi.org/10.2967/jnumed.125.270175 ...
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PET Imaging of the Human Brain with Microvolumetric Spatial Resolution

Journal of Nuclear Medicine September 2025, jnumed.124.268809; DOI: https://doi.org/10.2967/jnumed.124.268809 ...