Background Patients with Inflammatory bowel disease (IBD) have a high prevalence of depression. Gut microbiota dysbiosis has been reported to play an important role in IBD and depression. However, few ...

We read with great interest the study published by Boxhoorn et al , comparing lumen-apposing metal stents (LAMS) versus double-pigtail plastic stents (DPPS) for treatment of infected necrotising ...

Objectives We aimed to determine whether changes in acute severe colitis (ASC) management have translated to improved outcomes and to develop a simple model predicting steroid non-response on ...

Background and aims A previous study of ours indicated that enhancer of zeste homologue 2 (EZH2) plays an important role in hepatocellular carcinoma (HCC) tumorigenesis. The aim of the present study ...

BACKGROUND/AIM Proinflammatory cytokines are key factors in the pathogenesis of Crohn's disease (CD). Activation of nuclear factor kappa B (NFκB), which is involved in their gene transcription, is ...

IDDF2024-ABS-0381 Bacteroides fragilis toxin suppresses METTL3-mediated m6A modification in macrophage to promote inflammatory bowel disease ...

Liver fibrosis and cirrhosis result from the majority of chronic liver insults and represent a common and difficult clinical challenge of worldwide importance. At present, the only curative treatment ...

The mechanisms of wound healing in general have gained interest in recent years, as it has become obvious that the tightly regulated process of tissue repair and regeneration is of great importance ...

8 European Foundation for the Study of Chronic Liver Failure (EF CLIF), Barcelona, Spain Background Acute-on-chronic liver failure (ACLF) of various aetiologies is a complex syndrome with high ...

Background Anti-tumour necrosis factor α (TNFα) therapy effectively induces and maintains remission in Crohn's disease (CD). Up to 40% of patients, however, fail to respond to anti-TNFα. Objective To ...

We read with great interest the recent article by Tseng et al evaluating hepatitis B surface antigen (HBsAg) levels as a ...

Background —Peripheral arthropathy is a well-recognised complication of inflammatory bowel disease (IBD). Little is known of its natural history, but a variety of joint involvement has been described, ...