Conner Weigman threw for 305 yards and a touchdown and rushed for another score, Re'Shaun Sanford II and Mekhi Hughes added rushing scores and No. 23 Houston beat Oregon State 33-20 in the teams' season opener.

HOUSTON — The JaMarcus Shephard era begins with a loss, but the kind of competitive display that it has been sorely missing from Oregon State. The Beavers responded to an early score, then allowed 20 straight in what was setting up to be a rout for No.

The Beavers opened their season at No. 24 Houston Sept. 5, falling 33-20 in the opening game of the JaMarcus Shephard era.

The Oregon State Beavers visit the No. 24 Houston Cougars Saturday afternoon for a noon ET kickoff from TDECU Stadium in Houston, Texas.

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The Cougars are 21-point favorites in the latest Oregon State vs. Houston odds. The over/under for total points is 51.5. Before making any Oregon State vs. Houston picks, be sure to check out the Houston vs. Oregon State predictions from the SportsLine Projection Model .

Even though University of Houston and Oregon State were in a close game in the fourth quarter, ESPN still moved it to ESPNews to make way for the start of the Texas-Texas State game.

HOUSTON — Oregon State’s offensive line suffered a blow against Houston. Carter Guillame, who entered for starting left guard Nathan Elu, limped off the field with a left foot injury after OSU’s final possession of the first quarter Saturday afternoon at TDECU Stadium.