San Francisco 49ers linebacker Fred Warner says he has been playing through a fractured bone in his ankle since Week 4.

Christian McCaffrey and the 49ers travel to Buffalo to take on Josh Allen and the Bills for Sunday Night Football. Live ...

We thought San Francisco was poised for a massive second-half run after the Week 9 bye with Christian McCaffrey back, but the ...

The San Francisco 49ers are 5-6 entering their matchup with the Buffalo Bills on Sunday, and an NFL executive called out ...

The Pittsburgh Steelers and Cleveland Browns had one of the most picturesque games in NFL history last Thursday night when ...

Who plays whom in NFL Week 13? Take a look at the 16 games on the Week 13 NFL schedule this week, starting with three games ...

San Francisco has been up and down all season ... Check out expert picks and best bets for every NFL game this week. Buffalo ...

Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an ...

The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night.

The San Francisco 49ers are reeling and now head to Buffalo for a prime time game. Will they have their starting QB back in ...

Despite the fractured bone in his ankle, Warner has maintained his All-Pro caliber play through the first 12 weeks of the ...

The 49ers have dealt with injuries to key players all season. Brandon Aiyuk injured his knee, Brock Purdy missed last week's ...