No. 15 Baylor visits the No. 25 UConn Huskies after Jayden Nunn scored 23 points in the Bears' 91-60 win over the New Orleans Privateers.
The No. 20 North Carolina Tar Heels face the No. 10 Alabama Crimson Tide. The teams meet Wednesday for the first time this season.
The Florida Gulf Coast Eagles host Pjay Smith Jr. and the Furman Paladins. Wednesday's matchup is the first this season between the two teams.
Sacred Heart plays the Morgan State Bears after Ny'Ceara Pryor scored 23 points in Sacred Heart's 59-47 loss to the Coppin State Eagles.
American takes on the George Washington Revolutionaries after Matt Rogers scored 20 points in American's 97-52 win against the Notre Dame-Maryland Gators.
Northern Arizona visits the Oral Roberts Golden Eagles after Trenton McLaughlin scored 20 points in the Lumberjacks' 74-71 win over the Houston Christian Huskies.
Saint Louis takes on the San Francisco Dons after Gibson Jimerson scored 21 points in the Billikens' 74-66 win against the Jackson State Tigers.
Fresno State takes on the No. 24 San Diego State Aztecs after Amar Augillard scored 26 points in Fresno State's 86-81 overtime loss to the Cal Baptist Lancers.