The contraction of smooth muscle is an essential process underpinning diverse physiological functions ranging from gastrointestinal motility to vascular regulation. At its core, smooth muscle ...
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Genetic model reveals a form of calcium release is unnecessary for normal muscle contraction
The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role ...
In the avian embryo, vascular smooth muscle cells (VSMC) in the aortic arch (elastic) arteries originate in the neural crest, whereas other VSMC develop from local mesoderm. These two lineages have ...
A team of investigators from Massachusetts General Hospital (MGH), a founding member of Mass General Brigham (MGB) and Mass General for Children (MGfC) has identified - for the first time - the ...
β-Catenin phosphorylation plays important roles in modulating its functions, but the effects of different phosphorylated forms of β-catenin in response to heterocellular interaction are unclear. Here ...
Researchers engineered mice with a mutation (E3896A) in the RyR1 calcium-binding site, eliminating calcium-induced calcium ...
Obesity changes how airway muscles function, increasing the risk of developing asthma, a new study suggests. New research suggests that obesity changes how airway muscles function, increasing the risk ...
As food is digested and nutrients are absorbed, there is a lot of movement in the gut. Scientists have now shown that a protein called Piezo1 that acts as a pressure sensor in the body also works to ...
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