Background: We aimed to explore the clinical features and predictive factors for visual prognosis of neurosyphilis-associated optic atrophy (NSAOA ... thinner inferior peripapillary retinal nerve ...

Optineurin is linked to ALS and glaucoma, but the mechanism is unknown. Here, the authors show that optineurin mutation causes deficits in axonal mitochondria transport and neurodegeneration ...

Learn about the promising advance in prenatal treatment of spinal muscular atrophy, introducing a potential approach to suppress symptoms of the disorder in infants.

Optic atrophy involves damage (neurodegeneration) to the optic nerve that transmits visual signals from the eye to the brain. This damage results in visual impairment, and its restoration presents a ...

Optic nerve atrophy (ONA) is the result of various pathologies of the visual organ, in which the corresponding nerve is damaged. The optic nerve transmits visual signals from the retina to the brain, ...

Direct application of local estrogen to the vulvar vestibule, with the consideration of adding a local androgen as well, is important to adequately treat symptoms of vulvovaginal atrophy.

Optic Atrophy Type 1 (OPA1), a mitochondrial fusion protein ... the LC3-II/I ratio and the LAMP1 expression were increased in OPA1 overexpressed optic nerve. These findings suggest that OPA1 ...