and seropositive aquaporin-4 antibody (AQP4-Ab) (26) typically present in patients with optic neuritis. In the present cohort study, it was demonstrated that optic neuritis was followed by a ...

Correspondence to Jacqueline Palace, Department of Neurology, Oxford University Hospitals NHS Trust, West Wing Level 3, John Radcliffe Hospital, Oxford, OX39DU, UK; jacqueline.palace{at}ndcn.ox.ac.uk ...

ON = optic neuritis; OND = other neurological diseases Table 2. Clinical findings, AQP4-Ab status in serum and CSF, and median AQP4-Ab serum titres in the various disease groups.

med.tohoku.ac.jp Acute optic neuritis (ON) typically presents with ocular pain and ... Recently, we reported some distinct characteristics between seropositive anti-aquaporin-4 (anti-AQP4) patients ...

However, an orbital MRI highlighted optic neuritis in the right optic nerve ... mediated by B-cell humoral immunity disorders and possibly linked to AQP4 expression in the thymus gland, points to a ...

In this Healio Video Perspective from Hawaiian Eye 2025, Riad Sherif, MD, CEO of Oculis, discusses data on OCS-05 for the ...

Optic neuritis (ON) is an inflammation that damages your optic nerve. It can cause vision loss and pain when you move your eyes. As the inflammation goes away, your symptoms usually get better.

Other eye conditions, such as optic neuritis and diplopia, are also known to affect many people with MS. Optic neuritis is a common vision problem related to MS. It’s inflammation of the optic ...

Background: In 70-80% of cases, neuromyelitis optica (NMO) is associated with highly specific serum auto-antibodies to aquaporin-4 (termed AQP4-Ab or NMO-IgG). Recent evidence strongly suggests ...

Introduction: Optic neuritis (ON) is often an early sign of multiple sclerosis (MS), and recent studies show a link between HIF-1 pathway activation and inflammation. This study aimed to determine if ...