The 49ers have revealed their latest injury report before their Sunday Night Football tilt against the Buffalo Bills.

Deebo Samuel probably is the most disappointing player on the most disappointing team in the NFL through 12 weeks. Despite ...

San Francisco 49ers linebacker Fred Warner says he has been playing through a fractured bone in his ankle since Week 4.

Head coach Kyle Shanahan explains why the 49ers don't rotate their running backs to give Christian McCaffrey a breather.

49ers linebacker Fred Warner revealed Wednesday that he has played most of this season with a fracture in his ankle. Warner ...

The Buffalo Bills will have to wait and see what happens with tight end Dalton Kincaid as his status for this week is up in ...

San Francisco 49ers star Fred Warner told reporters Wednesday that he fractured an ankle on Oct. 29 and has been receiving ...

Fred Warner revealed for the first time Wednesday that he's been playing through a fractured bone in his ankle that he ...

Buffalo Bills coach Sean McDermott looked and sounded refreshed as he and his team returned from its bye week.

SANTA CLARA, Calif. (AP) — Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he ...

Brock Purdy threw one short pass in the open portion of practice for the San Francisco 49ers as he remains slowed by an ...

The AFC East-leading Buffalo Bills return from their bye week to host the inconsistent San Francisco 49ers on Sunday night.