Objectives To investigate the relationship between alcohol consumption and dementia. Design Prospective cohort and case–control analyses combined with linear and non-linear Mendelian randomisation.

Correspondence to Dr Fares Alahdab, Mayo Clinic Minnesota, Rochester MN 55905, USA; alahdab.fares{at}mayo.edu, fares.alahdab{at}gmail.com A surprisingly huge proportion of medical research still shows ...

Concern has been raised about whether HPV vaccines might cause serious neurological disorders including postural orthostatic tachycardia syndrome (POTS) and chronic regional pain syndrome (CRPS). The ...

Registration of health and medical research is an effective way of improving the transparency and credibility of evidence. Registration involves pre-specifying the research objectives, design, methods ...

Background Musculoskeletal knee pain is a large and costly problem, and meniscal tears make up a large proportion of diagnoses. ‘Special tests’ to diagnose torn menisci are often used in the physical ...

Correspondence to Sir Iain Chalmers, James Lind Initiative, Summertown Pavilion, Middle Way, Oxford OX2 7LG, UK; ichalmers{at}jameslind.net We are surrounded by maelstroms of claims about the effects ...

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be ...

Correspondence to Professor Carl Heneghan, Primary Care Health Sciences, University of Oxford, Oxford OX1 2JD, UK; carl.heneghan{at}phc.ox.ac.uk If you wish to reuse ...

Health technology assessment in India in the next decade: reflections on a vision for its path to maturity and impact ...

Objectives Internationally there appears to be two distinct themes emerging in relation to diagnosis. One, initiated by the Improving Diagnosis in Health Care-report in 2015 focuses on avoiding ...

Correspondence to Dr Sietse Wieringa, Centre for Sustainable Healthcare Education, University of Oslo, Oslo, Norway; c.h.s.wieringa{at}medisin.uio.no Over time, an international consensus on ‘best ...

Correspondence to Professor Johan Sundström, Department of Medical Sciences, Uppsala Clinical Research Center, Uppsala 751 85, Sweden; johan.sundstrom{at}medsci.uu.se When a high-risk person is ...