Loss of functional adenomatous polyposis coli (APC) protein results in the stabilization of cytosolic β-catenin and activation of genes that are responsive to Lef/Tcf family transcription factors. We ...
Programed cell death 4 (Pdcd4) is a novel tumor suppressor that frequently exhibits downregulated expression in several types of cancer. In colon cancer tissues, expression level of Pdcd4 is ...
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