As common as depression is—about one person in 10 experiences depression in any given year—it still eludes complete understanding. There does not seem to be a single cause; rather many factors ...

The core experiences of depression — changes in energy, activity, thinking, and mood — have been described for more than 10,000 years. The word “depression” has been used for about 350 years. Given ...

Depression is a complex and deeply personal experience. While almost everyone has periods of sadness, low mood or grief, depression is different. Major depressive disorder is persistent, interferes ...

Patients with type 2 diabetes often have comorbid major depressive disorder, but the underlying neurobiological substrates are still poorly understood. The goal of this study was, therefore, to ...

Since the 1960s, researchers have postulated that major depression stems from disruptions in the serotonin neurotransmitter system, but the evidence for that idea, though plentiful, was indirect. In ...

Bill Valvo could sense that something was going very wrong with his health. He had worked for a software-development company in Fairfax, Va., for 10 years following a 22-year hitch with the Air Force, ...

Depression is characterized by a persistent low mood that can affect quality of life. If symptoms usually only occur in the winter months, it may be seasonal affective disorder (SAD), or major ...

Depression is a common emotional state that many people have experienced at some point in their life. For some, depression is a diagnosis and the one thing that they can't seem to shake despite trying ...

Although depression most often arises in response to some kind of defeat, depression can seem to arise out of the blue, for no obvious reason. It may even arise when life appears to be going extremely ...

Depression is a state of unhappiness and hopelessness - a psychiatric disorder manifested by persistent feelings of dejection, lack of energy, poor concentration and sometimes suicidal thoughts. There ...