Can networks of genes be stimulated using resonance? Researchers at the Niels Bohr Institute are investigating whether the ...

This review illustrates how the nuclear phosphoinositide-p53 signalosome integrates lipid signaling and p53 function to regulate cancer cell motility. The figure contrasts the tumor-suppressive ...

The p53 protein, is a tumor suppressor often inactivated in cancers by gene mutations or the inhibition by overexpressed MDM2 and MDM4 (X). Pharmacological reactivation of wild-type p53 protein, or ...

In a recent study published in the Cell Reports journal, researchers assessed the impact of protein adduction on p53 tumor suppressor inhibition. Studies have shown that exposing esophageal cells to ...

Scientists discover how the Fas-p53 pathway sabotages energy metabolism, offering new hope for tackling obesity and improving insulin sensitivity. Brief Communication: Expression of p53 in human ...