which may or may not be restricted to a single organ. Evidence for the 'single initiating antigen' hypothesis is provided by the observation that autoimmune diseases are often tissue-specific and ...

These can be categorised into systemic autoimmune diseases, and organ-specific autoimmune diseases. “Systemic autoimmune diseases, like systemic lupus erythematosus (SLE) and rheumatoid ...

A revolutionary approach to immune therapy has emerged: engineered immune cells that protect healthy tissue without ...

Autoimmune diseases are characterized by an inappropriate immune response to healthy organs and tissues in the body. For example, many people with RA have autoantibodies that attack healthy joint ...

Despite progress in the field of organ transplantation for improvement ... role of alloimmune responses to donor-specific antigens and autoimmune responses to tissue restricted self-antigens ...

Nearly every disease has an inflammatory component, but blood tests can't pinpoint inflammation in specific organs or tissues in the human body.

such as what happens in autoimmune diseases like lupus, after these immune cells see specific antigens they perceive as a threat. He said this demonstrates tremendous specificity, making this ...

They used genetically engineered mice lacking specific ... the immune system stimulates the production of the hormone glucagon by sending immune cells on a journey across different organs”.

Crohn’s disease isn’t just about digestion. From joint pain to vision issues, its hidden symptoms affect the body in unexpected ways.

Researchers discovered a previously unknown mechanism that may drive tissue damage and a new target for drug discovery.

The first clinical trials using organs from genetically modified pigs offer hope to patients with kidney failure, who face a ...