A teenage girl presented to the hospital emergency department with a three-week history of intermittent frontal headache, which was worse in the morning and associated with nausea, vomiting, lethargy, ...

Demyelinating optic neuritis (DON) is a hallmark feature of ... but no pain. MS demyelinating lesions involving the retrochiasmal visual pathways are most often asymptomatic.

Optic neuritis occurs frequently in patients with ... but are frequently asymptomatic and usually result from large lesions involving the optic radiations. Focus Point #4 Ocular inflammation ...

Demyelinating lesions can affect different parts of ... Other eye conditions, such as optic neuritis and diplopia, are also known to affect many people with MS. Optic neuritis is a common vision ...

Optic neuritis (ON) is an inflammation that damages your optic nerve. It can cause vision loss and pain when you move your eyes. As the inflammation goes away, your symptoms usually get better.

In this Healio Video Perspective from Hawaiian Eye 2025, Riad Sherif, MD, CEO of Oculis, discusses data on OCS-05 for the ...

Changes to cerebrospinal fluid (CSF) also are evaluated. Optic neuritis—inflammation of one of your two optic nerves—is a common first presentation of MS. In fact, CIS may be diagnosed from an ...

Neuropathological analysis of such lesions revealed apoptotic neurons ... as observed in rat retinal neurons during optic neuritis induced by immunization with myelin oligodendrocyte glycoprotein.

OCS-05 demonstrates safety and efficacy in treating acute optic neuritis, receiving FDA IND clearance for clinical development in the U.S. Small sample size of only 36 patients in the Phase 2 ...