WHILE examining the histochemistry of the optic nerve, we observed beaded transverse band-like areas, which were more dense than the other areas in the myelin sheath in osmium-tetroxide-fixed tissues ...

Multiple sclerosis (MS) is an autoimmune demyelinating disease of the central nervous system that commonly causes optic neuritis. While people with MS can initially recover from optic neuritis, over ...

The dehydration of rat optic nerve has been studied by allowing specimens to become partially or fully dried before fixation and preparation for electron microscopy. A correlation is established ...

A PREVIOUS study of oxidative enzyme activity in the macroglia of adult cat optic nerve 1 has shown that α-glycerophosphate dehydrogenase (GPDH) activity which is not linked to NAD is localized ...

Electron microscope image of a nerve fiber with myelin (in black) in the optic nerve of an MS patient. In yellow, the spaces between myelin layers that are enlarged in MS) Disclaimer: AAAS and ...

Observing the structure and regeneration of the myelin sheath in peripheral nerves following injury and during repair would help in understanding the pathogenesis and treatment of neurological ...

Research results suggest that the inhibition of phosphorylation of microtubule-binding protein CRMP2 could be a novel approach to the development of treatments for optic neuropathies, such as glaucoma ...

A new report examined optic nerve lesion length, measured on brain magnetic resonance imaging, at the acute phase of ON in 51 individuals. Optic nerve lesion length was significantly associated with ...

Biomedical scientists reports a drug -- an estrogen receptor ligand called indazole chloride (IndCl) -- has the potential to improve vision in patients with multiple sclerosis, or MS. The study was ...

Multiple sclerosis is a chronic, often disabling, neurological disease that affects the central nervous system (the brain, optic nerves and the spinal cord). The disease most commonly causes relapses, ...