NETs promote macrophage expression of T-cell chemokines and subsequently facilitate cytotoxic CD8+ T cell infiltration and granzyme B production, which drives kidney fibrosis in obstructive ...

In a recent study published in the Journal of Biomedical Science, researchers investigate whether M2 macrophage-derived exosomes (M2-Exos) could prevent inflammation-associated damage during ...

Neutrophils induce anti-inflammatory -- or M2 -- macrophages deep in their granulocyte core. The dense globular structures of granulomas in animals, particularly in the lungs, have been studied.

Liver transplants save the lives of many people, but the procedure can result in severe complications. One of these common side effects is liver ischemia-reperfusion injury (LIRI), in which the oxygen ...

The effects of sargramostim and filgrastim on hematopoietic cells are described. Filgrastim is a lineage-specific colonystimulating factor (CSF), mainly affecting neutrophils. In addition to enhancing ...

Neutrophils have been shown to puncture stressed heart cells after a heart attack via a resistin-like protein, leading to deadly arrhythmias.

At the height of the SARS-CoV-2 pandemic, researchers in Thomas Marichal’s immunophysiology laboratory at the University of Liège were studying samples collected from the lungs of patients who had ...

In a recent study published on the medRxiv* preprint server, researchers map the proteomes of peripheral blood neutrophils isolated from hospitalized coronavirus disease 2019 (COVID-19) patients using ...

Kyoto, Japan -- When our bodies become infected, various immune responses are triggered, starting with a release of granulocytes, white blood cells containing special enzymes that make up about half ...