Germ-line mutations in the base-excision–repair gene MYH have been associated with recessive inheritance of multiple colorectal adenomas. Tumors from affected persons displayed excess somatic ...
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Classification of a VUS in MLH1 using a combination of family segregation studies and protein biochemistry. Predicting risk of chemotherapy-induced side effects in patients with colon cancer with ...
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343 Background: MYH-associated polyposis is an autosomal recessive syndrome caused by biallelic mutations in the base excision repair gene MYH. Initial reports indicated that a majority of European ...
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