The course explains the answers to the following questions: What is lipophilicity and why it is important? What type of lipophilicity is used in drug discovery (octanol/water, chromatographic and ...

Observational studies have suggested that statin use reduces the risk of Alzheimer disease, but the mechanism that underlies this association is unknown. Hypothetically, lipophilic statins could ...

This is a preview. Log in through your library . Abstract The history of the relationship of biological activity to partition coefficient and related properties is briefly reviewed. The dominance of ...

A molecule’s hydrophilicity or lipophilicity is a key physicochemical property, especially in the pharmaceutical industry due to its impact on the distribution of drug-like molecules within the body.