Pathogens or pathogen-associated molecular patterns can signal to cells of the innate immune system and trigger effective adaptive immunity. However, relatively little is known about how the innate ...
Heat shock 70 kDa proteins (HSP70s) are ubiquitous molecular chaperone machines, with the core consisting of an HSP70, a J protein and a nucleotide exchange factor (NEF). These machines function in a ...
A so-called "molecular chaperone", the protein Hsp70, carries out more functions in the maturation of proteins than previously thought. As the researchers have discovered, Hsp70 not only acts as a ...
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