A recent study from the Institute of Biomedicine at the University of Eastern Finland shows that the glucocorticoid receptor can both promote and inhibit prostate cancer progression, depending on the ...

Glucocorticoid receptors (GRs) are ligand-activated transcription factors that play a pivotal role in mediating the effects of endogenous and synthetic glucocorticoids. These receptors regulate a ...

New research from the University of Eastern Finland sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance ...

Glucocorticoids —such as cortisone— are among the most widely used anti-inflammatory drugs, and are used to treat asthma, psoriasis, organ transplantation and even COVID-19. Regarding their ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 116, No. 26 (June 25, 2019), pp. 13097-13106 (10 pages) Stress can either promote or impair learning and memory.

New research sheds light on the significance of the glucocorticoid receptor in drug-resistant prostate cancer, showing that the development of drug resistance could be prevented by limiting the ...

Deciphering how the GR forms oligomers — through the binding of several subunits — opens a crucial avenue for developing more selective drugs. These new drugs could modulate this association and thus ...

Drugs we take like prednisone can weaken our bones and so can aging, and scientists working to prevent both have some of the first evidence that the best target may not be the logical one. They are ...