Study argues to move beyond ‘reading genes’ — focus on conserved neural-development networks in humans to improve early screening and identify therapeutic leads.

Gene therapy has been successfully used to treat a number of diseases, including immune deficiencies, hereditary blindness, ...

Inside every cell, thousands of molecular signals collide, overlap, and compensate, obscuring the true drivers of gene expression.

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

A team led by Professor Shoichiro Asayama at Tokyo Metropolitan University has synthesized a charge-free molecule designed to sneak plasmid DNA into living cells via hydrogen bonding, dramatically ...

Getting DNA into a living cell sounds simple, until you remember the cell’s outer membrane acts like a guarded wall. DNA strands carry a negative charge, and they do not cross that wall easily.

Researchers develop synthetic markers that cross the blood-brain barrier, allowing for noninvasive monitoring of the living brain via blood tests.

Cardiovascular disease remains the leading cause of mortality worldwide, necessitating deeper insights into its molecular ...

Human metabolism is regulated by internal clocks, the so-called circadian rhythms. Many processes, such as sugar uptake, fat ...

Human DNA constantly refolds in 3D space, and these looping dynamics regulate gene expression and cell identity.