Ischemia reperfusion injury (IRI) is one of the main cause of organ dysfunction after heart attack and solid organ transplantation, and occurs frequently when the new organ comes from a deceased ...

Connexons form the basis of hemichannels and gap junctions. They are composed of six tetraspan proteins called connexins. Connexons can function as individual hemichannels, releasing cytosolic factors ...

In their May 2015 Scientific American article “Cellular Small Talk,”Dale W. Laird, Paul D. Lampe and Ross G. Johnson report on recent discoveries showing that the disruption of cellular structures ...

Neighboring cells exchange molecular information via channels that directly connect them. Disruption of this signaling system can lead to disorders ranging from hearing loss to heart disease Like ...

Researchers studying a critical stage of pregnancy -- implantation of the embryo in the uterus -- have found a protein that is vital to the growth of new blood vessels that sustain the embryo. Without ...

A new study by the University of California, Davis, shows how cells work together to avoid a sudden drop in blood sugar. Understanding these feedback loops could improve the lives of people with ...