GABA receptors, long recognised principally for their role in modulating neuronal excitability within the central nervous system, are now emerging as pivotal regulators of immune function. These ...

Scientists have revealed the molecular structure of a type of receptor that's crucial to brain development and function. 'This study shows the dominant assemblies and states of the GABA receptor. That ...

CHAMPAIGN, Ill. — Depression is a complex condition correlated with multiple differences in brain function and mechanisms. A new paper spanning known data about the neurotransmitter GABA and its ...

Fragile X syndrome (FXS) is the most common inherited form of intellectual disability. The cause, which has been well-studied, is the loss of fragile X mental retardation protein (FMRP)—a genetic ...

F. Hoffmann-La Roche Ltd. and Hoffmann-La Roche Inc. have synthesized GABA-A receptor γ1 subunit positive allosteric modulators (PAMs) reported to be useful for the treatment of cognitive and ...

Monica Joanna Elnekaveh's advocacy began when Eleanor was initially diagnosed with two mosaic gaba receptor gene deletions (GABRA1 and GABRG2). Driven by the urgent need for treatments, Monica founded ...

Korean researchers identify MAOB–GABA brake hindering spinal cord recovery and test drug New drug shows promise in restoring nerve growth by blocking astrocyte-produced GABA after spinal injury ...

Spinal cord injuries caused by external trauma, such as traffic accidents or falls, often lead to the permanent loss of motor and sensory functions. This is because the spinal cord—the central pathway ...