While most enzymatic activity is conducted through chemical binding interactions between molecules, in some cases, the mere presence of an enzyme can affect intracellular functions. While exploring ...
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The enzyme that doesn't act like one: NUDT5 controls DNA building block production through structure, not catalysis
Inside every cell, a finely tuned metabolic network determines when to build, recycle, or stop producing essential molecules. A central part of this network is folate metabolism, a process that ...
Dihydropteroate synthase (DHPS) is a crucial enzyme in the folate biosynthetic pathway, catalysing the formation of essential folate cofactors that underpin DNA synthesis and cellular functioning.
NUDT5 enzyme acts as a molecular scaffold that maintains metabolic balance. Inside every cell, a finely tuned metabolic network determines when to build, recycle or stop producing essential molecules.
Just when you thought you had your vitamins figured out, science throws us a curveball. New research from Texas A&M University is challenging everything we thought we knew about folate (that’s vitamin ...
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Folate deficiency drives genetic changes linked to lung cancer
Genetic alterations lie at the heart of cancer development, but scientists may have been overlooking a powerful driver of these changes—the everyday nutrients that feed our cells.
Folate, or vitamin B9, is an essential nutrient. Without it, individual cells could not replicate their DNA or make copies of themselves, and consequently, the body would not be able to grow or ...
Folate, otherwise known as vitamin B9, acts as a one-carbon cofactor for deoxyribonucleic acid (DNA) synthesis, repair, and methylation. It participates in interconnected folate and methionine cycles ...
Although they number from 1 (thiamine) to 12 (cobalamin), there are eight B vitamins—don't bother seeking numbers 4, 8, 10, or 11. The rest are all facilitators of the nervous system and tend to work ...
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