A polygenic risk score (PRS) based on genes associated with endothelial cell function identifies patients at a higher risk of coronary artery disease, according to a new study. The risk score, which ...

The glycocalyx emerges as an active endothelial system whose structure, metabolism, and shear-dependent regulation integrate mechanical forces with vascular signaling. Disruption of this system ...

Each year in the U.S., approximately 2.5 million people suffer traumatic brain injuries (TBIs). About 50,000 of these injuries will result in death, and more than 80,000 will lead to permanent ...

Jillian Richter, Ph.D., an associate professor in the Division of Trauma & Acute Care Surgery published “Trauma promotes heparan sulfate modifications and cleavage that disrupt homeostasis gene ...

Sepsis, a life-threatening systemic inflammatory response triggered by infection, has long challenged clinicians with its persistently high mortality (up to 40-50% in septic shock). At the heart of ...

A new blood test approach could detect vascular damage earlier than ever before, helping identify heart and kidney disease ...

The expanding field of short peptide bioregulators has generated sustained interest in recent decades, particularly in ...