Does jammed-up protein recycling in neurons cause proteins to spill into the cerebrospinal fluid in Alzheimer’s disease? As reported in the November 25 Science Translational Medicine, scientists led ...
A recent study posted to the bioRxiv* preprint server assessed the role of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron spike H655Y mutation on viral entry pathways. Study: ...
A lipid nanoparticle (LNP) containing messenger RNA (mRNA) enters a cell through an endosome (right). When the LNP is inside the acidic endosome (middle), the ionizable lipids become positively ...
Dysfunctional presenilin 1, infamous for misprocessing the amyloid precursor protein in familial Alzheimer’s disease, isn’t a one-trick pony. PS1 variants also weaken lysosomes, slow endosomal ...
Collaborative research at the University of Cincinnati has developed a new probe to better study cells that has already led to new knowledge about certain cellular processes. UC's Jiajie Diao, PhD, ...
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