Puppies are already irresistible, but combining two stunning breeds results in a litter that's beyond adorable. In a TikTok video uploaded by Slove126 (@slove126) a precious posse of Great ...

The breed is known for having large litters, usually an average of 7.1 puppies, according to Rover.com. Representatives of Perfectly Imperfect Pups said it was the largest litter they’ve ever seen, ...

The average Great Dane litter is 10 puppies. Cleo, a Great Dane in Arizona, was said to be doing well Monday after giving birth to 19 -- yes, 19 -- puppies over the weekend. Doctors at the Kingman ...

A Great Dane that died in 1990 helped conceive a litter of puppies born on Valentine's Day, KHOU reported. Topper was a Great Dane born in 1980. His owner, Marilyn Herdejurgen, had the dog’s semen ...

HOUSTON — It’s a Houston miracle times nine. A litter of puppies were fathered by a dog born 29 years ago. The puppies were conceived using frozen semen from a champion Great Dane named Topper who ...

RALEIGH, N.C. (WNCN) – A Great Dane named Meadow just gave birth to the largest-ever litter observed by a North Carolina rescue. Meadow, who was taken in by Perfectly Imperfect Pups in Raleigh just ...

The mom and all of her puppies are alive, healthy and doing well Kelli Bender is the Pets Editor at PEOPLE. She has been working at PEOPLE since 2013. Her work has previously appeared on MTV, The ...

RALEIGH, N.C. (Gray News) – An animal rescue in North Carolina took in a pregnant Great Dane who would give birth to 15 puppies a few days later. Perfectly Imperfect Pups in Raleigh took in the dog on ...