Open-source software unlocks rapid DNA structure generation and analysis in one workflow

Computational chemists at the University of Amsterdam's Van 't Hoff Institute for Molecular Sciences have developed a ...
News Medical

Unusual i-DNA structure shown to regulate genes and cancer

DNA's iconic double helix does more than "just" store genetic information. Under certain conditions it can temporarily fold into unusual shapes. Researchers at Umeå University, Sweden, have now shown ...

In 1953, scientists pieced together a twisted molecule, and DNA finally had a shape

Scientists uncovered DNA's double helix structure in 1953. James Watson and Francis Crick proposed the model. It explained ...
PBS

The Discovery of DNA's Structure:

They were hardly modest, these two brash young scientists who in 1953 declared to patrons of the Eagle Pub in Cambridge, England, that they had "found the secret of life." But James Watson and Francis ...
Nanowerk

What is DNA Origami? Structure, Design and Applications

In one sentence: DNA origami is a self-assembly technique that folds a long single-stranded DNA molecule into precisely defined nanoscale shapes using hundreds of short, computer-designed staple ...
Phys.org

Study explores limits of DNA structure and function, may expand use of modified DNA in medicine

A team led by Professor Michal Hocek at IOCB Prague has explored the limits of the structure and function of DNA and successfully pushed forward known boundaries. Their latest research has just been ...
Phys.org

Researchers decode tertiary structure of DNA aptamer–ATP complex and improve binding affinity

DNA aptamers are powerful molecular tools in biosensing, bioimaging and therapeutics. However, a limited understanding of their tertiary structures and binding mechanisms hinders their further ...
Nature

CryoREAD provides fully automated DNA–RNA structure modeling for cryo-EM maps

Identifying the three-dimensional (3D) structures of macromolecules is essential for understanding their biological functions as well as their applications in drug design and molecular engineering. To ...
The Conversation

Unravelling DNA’s structure: a landmark achievement whose authors were not fairly credited

Seventy years ago, two male scientists, Francis Crick and James Watson, proclaimed they had discovered the secret of life: the structure of DNA. Since then, history has acknowledged how Rosalind ...

UT Austin researchers create nanoscale Longhorn using DNA origami

UT Austin researchers folded DNA into a nanoscale Longhorn, demonstrating a breakthrough that could help deliver cancer drugs ...
Nature

Kinetoplast DNA structure, RNA editing patterns and small respiratory Complex I in Trypanosoma musculi

Trypanosomes are a diverse group of single-celled eukaryotes, and include significant human and livestock pathogens responsible for severe diseases such as Human African Trypanosomiasis and Chagas ...
Wall Street Journal

James Watson, Who Co-Discovered DNA Structure, Dies at 97

James Watson, the scientist who became famous for helping discover the structure of DNA in 1953 and notorious decades later for suggesting that Black people are intellectually inferior to whites, has ...