Cyclodextrin has been shown in mice to dissolve cholesterol crystals and prevent plaque formation. The drug is already approved for use in humans and could be tested in patients to treat ...

Two parents’ quest to save their twin daughters’ lives from a rare, degenerative genetic disorder may end up saving and improving the lives of millions. After digging through medical literature and ...

Chemists have a sweet spot for cyclodextrin (CD) rings, cyclic molecules made of glucose sugars linked together like dancers in a Henri Matisse painting. Cyclodextrins have found use as drug delivery ...

A sugar that freshens air in rooms may also clean cholesterol out of hardened arteries. The sugar, cyclodextrin, removed cholesterol that had built up in the arteries of mice fed a high-fat diet, ...

Chemists love to tinker with cyclodextrins (CDs)—macrocyclic daisy chains of glucose molecules that feature a hydrophobic core surrounded by a hydrophilic exterior. They’ve been used to encapsulate ...

Krabbe disease, also called globoid-cell leukodystrophy, is caused by a deficiency of the lysosomal enzyme β-galactosylceramidase (GALC), resulting from pathogenic variants in both copies of the GALC ...

Cyclodextrine wurden vor mehr als 100 Jahren entdeckt, sind aber aktueller denn je. Besonders ihre Derivate stellen interessante Hilfsstoffe dar, die nicht nur in der Arzneimittelentwicklung, sondern ...