Triglycerides, a type of fat essential for energy, become a hidden danger when levels rise too high. Chronically elevated ...

Lipoprotein (a) is a fatty particle that circulates in the blood and deposits cholesterol in the arteries contributing to ...

The triglyceride glucose index may predict adverse cardiovascular outcomes in patients with acute myocardial infarction (AMI) and well-controlled cholesterol levels after percutaneous coronary ...

Reducing the levels of triglycerides and triglyceride-rich lipoproteins remains an unmet clinical need. Olezarsen is an antisense oligonucleotide targeting messenger RNA for apolipoprotein C-III ...

Familial chylomicronemia syndrome is a genetic disorder associated with severe hypertriglyceridemia and severe acute pancreatitis. Olezarsen reduces the plasma triglyceride level by reducing hepatic ...

Higher triglyceride levels — a main energy source for the brain — are associated with lower risk for dementia that is not mediated by age, sex, or APOE-ε4 allele status, a large study of ...

Both doses of olezarsen significantly reduced triglyceride levels at 6 months compared with placebo (placebo-adjusted reduction, 50mg: 58%; 80mg: 61%; P .0001). Topline data were announced from a ...

Ionis Pharmaceuticals has hit a “home run,” according to analysts at Citi, with data in two phase 3 trials that show the ability of Tryngolza (olezarsen) to reduce triglycerides and acute pancreatitis ...

CRISPR Therapeutics has reported reductions in triglycerides and LDL cholesterol of more than 80% after a single dose of its in vivo liver editing prospect CTX310, encouraging the company to forge ...

CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced positive topline results from the Essence study of olezarsen in people with moderate hypertriglyceridemia ...