Lipoprotein (a) is a fatty particle that circulates in the blood and deposits cholesterol in the arteries contributing to ...
Reducing the levels of triglycerides and triglyceride-rich lipoproteins remains an unmet clinical need. Olezarsen is an antisense oligonucleotide targeting messenger RNA for apolipoprotein C-III ...
The triglyceride glucose index may predict adverse cardiovascular outcomes in patients with acute myocardial infarction (AMI) and well-controlled cholesterol levels after percutaneous coronary ...
Triglycerides, a type of fat essential for energy, become a hidden danger when levels rise too high. Chronically elevated ...
Higher triglyceride levels — a main energy source for the brain — are associated with lower risk for dementia that is not mediated by age, sex, or APOE-ε4 allele status, a large study of ...
Familial chylomicronemia syndrome is a genetic disorder associated with severe hypertriglyceridemia and severe acute pancreatitis. Olezarsen reduces the plasma triglyceride level by reducing hepatic ...
Both doses of olezarsen significantly reduced triglyceride levels at 6 months compared with placebo (placebo-adjusted reduction, 50mg: 58%; 80mg: 61%; P .0001). Topline data were announced from a ...
Ionis Pharmaceuticals has hit a “home run,” according to analysts at Citi, with data in two phase 3 trials that show the ability of Tryngolza (olezarsen) to reduce triglycerides and acute pancreatitis ...
CARLSBAD, Calif.--(BUSINESS WIRE)--Ionis Pharmaceuticals, Inc. (Nasdaq: IONS) today announced positive topline results from the Essence study of olezarsen in people with moderate hypertriglyceridemia ...
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