Using laser microsurgery and cell fusion we have explored how additional centrosomes and/or chromosomes influence the duration of mitosis in human cells. We found that doubling the chromosome number ...

Researchers provide insight into an old mystery in cell biology, and offer up new clues to understanding cancer. Scientists have unraveled the mystery of how cells count the number of centrosomes, the ...

For almost a century, our understanding of the tiny structure at the centre of the cell called the centrosome was limited to its ability to organize mitotic spindles and other microtubule arrays.

When a cell is dividing, two identical structures, called centrosomes, move to opposite sides of the cell to help separate its chromosomes into the new cells. When a cell is dividing, two identical ...

When cells extend, move, or divide, a tiny organelle called the centrosome provides a cytoskeletal anchor and regulatory hub. It was long held that centrosomes are similar in composition across cells.

The centrosome is the organelle responsible for the organization of the cytoskeleton during cell division, an essential function in organisms from yeast to humans. Until now, scientists assumed that ...

Centrosomes are small structures in cells with many essential functions, including roles in cell signaling and in organizing a cell’s cytoskeleton. Centrosome dysfunction contributes to diseases like ...

Unseen and ongoing, thousands of times every second: to keep a complex organism like humans alive, an immense number of new cells must be continuously produced. Up close, each of these cell divisions ...

A tiny, freshwater flatworm found in ponds and rivers around the world that has long intrigued scientists for its remarkable ability to regenerate has now added a new wrinkle to biology. The ...

The story of the cell cycle is often told only through the perspective of the chromosomes as they replicate and then divide. This resource beautifully illustrates the role of the cytoskeleton in that ...

The mystery of how cancers build up resistance mechanisms and evade the treatments that should have destroyed them is a hugely pressing question. Overcoming cancer treatment resistance—a phenomenon ...