One of the fundamental biological processes in life is the cell cycle leading from DNA replication to cell division. While it has been studied for decades and our knowledge has matured, sophisticated ...

J. Gautier, M.J. Solomon, R.N. Booher, J.F. Bazan, M.W. Kirschner, "cdc25 is a specific tyrosine phosphatase that directly activates p34 cdc2," Cell, 67:197-211, 1991 ...

The awe-inspiring process of cell division can turn a fertilized egg into a baby – or a cancerous cell into a malignant tumor. With so much at stake, nature keeps it tightly controlled in a process ...

Every day, our bodies perform around 330 billion cell divisions to keep us alive and functioning. These divisions rely on the cell cycle, which has been in place since the earliest bacteria. The ...

Every day, our bodies perform around 330 billion cell divisions to keep us alive and functioning. These divisions rely on the cell cycle, which has been in place since the earliest bacteria. The ...

Every day, our bodies perform around 330 billion cell divisions to keep us alive and functioning. These divisions rely on the cell cycle, which has been in place since the earliest bacteria. The ...

Using an innovative scientific approach, scientists have obtained a wealth of new data on many of the proteins responsible for regulating the cell cycle – a sequence of molecular events that ...

The review emphasizes how breakthroughs in understanding the molecular mechanisms of cell cycle regulation have paved the way for the development of targeted anti-cancer agents. Notably, inhibitors of ...

The two articles describe the physical interactions between the retinoblastoma protein and D cyclins, a basic discovery in cell biology that has ramifications for the study of cancer. Both types of ...