GPCRs are involved in various physiological processes, such as the regulation of behavior, mood, and immune system activity. GPCRs represent one of the most important targets in drug discovery; ...
For decades, dopamine signaling was viewed primarily through the lens of motor vigor—how fast or forcefully one moves. However, a landmark 2025 study from Karolinska Institutet published in Nature ...
G protein-coupled receptors (GPCRs) represent a diverse group of signaling proteins and are involved in a wide variety of physiological processes. Of particular importance to the pharmaceutical ...
Thought LeadersEdoardo FabiniPrincipal Scientist Evotec U.K. G-protein-coupled receptors (GPCRs) play a pivotal role in cellular signaling and have long been a major focus in drug discovery. These ...
This article and associated images are based on a poster originally authored by Sam Hoare, Luciana Leo, Anastasia Schultz, and Thom Hughes and presented at ELRIG Drug Discovery 2025 in affiliation ...
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