Associate Professor, Case Western Reserve University School of Medicine; Clinical Specialist in Family Medicine, University Hospitals, Case Medical Center, Cleveland, Ohio; Associate Clinical ...
Background: Buspirone is a partial 5-HT 1A receptor agonist. Animal studies have shown that modulation of serotoninergic transmission at the 5-HT 1A receptor can induce analgesia in acute pain models.
Five male rhesus monkeys (Macaca mulatta) that weighed between 6 and 10 kg were studied. All monkeys had a history of cocaine self-administration. Each day, monkeys received multiple vitamins, fresh ...
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