San Francisco 49ers star running back Christian McCaffrey believes Isaac Guerendo can make an impact in the upcoming season.

The San Francisco 49ers plan to leave the Bay Area more than a week before they play the Los Angeles Rams in Melbourne, Australia.

San Francisco 49ers running back Christian McCaffrey was inspired by Conor McGregor's movement coach in his preparation for ...

San Francisco 49ers head coach Kyle Shanahan provided updates on player health and early offseason progress as the 49ers ...

The San Francisco 49ers made a few roster moves on Thursday after one running back went down with a long-term injury.

The San Francisco 49ers kicked off OTA's, on Wednesday. The team has had almost full turnout for the voluntary workouts, ...

Shanahan's latest comments came after NFL Commissioner Roger Goodell responded to the coach's initial concerns ...

OTAs for the NFL began this week, but the injury bug has already hit the 49ers’ locker room. When coach Kyle Shanahan met ...

The San Francisco 49ers have three preseason matchups before Week 1, and they'll hold joint practice sessions with two of ...

The 49ers shared key OTA injury updates on Nick Bosa, George Kittle, Isaac Guerendo, and Mac Jones after Thursday's practice.

Another San Francisco player has gotten injured, and the 2026 season isn't even underway yet The post 49ers Injury Woes Begin ...

A beloved former member of San Francisco's organization has passed away The post 3-Time Super Bowl Champion 49ers Coach Dies ...