The most common adverse events reported with both treatments were mild to moderate gastrointestinal-related side effects.
In the trail, 11 participants in the azelaprag group exhibited transaminase elevations without significant symptoms.
GP leaders have warned that the rollout of the weight loss drug tirzepatide (Mounjaro, Eli Lilly) will still have ...
BioAge Labs halts STRIDES Phase 2 trial of azelaprag after liver enzyme elevations, plans further analysis with updates ...
Those treated with tirzepatide, a dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1 receptor agonist, lost on ...
Tirzepatide has been shown in clinical trials to be more effective than diet and exercise support alone, and when compared ...
Following its endorsement of Eli Lilly’s obesity medicine tirzepatide, England’s National Institute for Health and Care ...
Tirzepatide reduced cardiovascular death or heart failure worsening by 38% in patients with obesity and HFpEF, compared to placebo. The trial showed significant weight loss and improved insulin ...
Obesity is chronic disease and causal precursor to myriad other conditions, including type 2 diabetes. In an earlier analysis of the SURMOUNT-1 trial, tirzepatide was shown to provide substantial ...
Tirzepatide also had meaningful and significant effects on health status, exercise tolerance, and systemic inflammation. "SUMMIT is the first trial in patients with HFpEF and obesity that had ...
Data continue to show that tirzepatide, called Mounjaro for type 2 diabetes and Zepbound for weight loss, is safe and effective, but side effects remain.